|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 124 and 396 of ATG16L1 (Uniprot ID#Q676U5)|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-34766 targets ATG16L1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-34766 immunogen is recombinant fragment corresponding to a region within amino acids 124 and 396 of ATG16L1 (Uniprot ID#Q676U5).
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 . Several transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: APG16-like 1; APG16L; APG16L beta; ATG16 autophagy related 16-like 1; ATG16A; ATG16L; autophagy related 16-like 1; Autophagy-related protein 16-1; IBD10; WD repeat domain 30; WDR30
Gene Aliases: APG16L; ATG16A; ATG16L; ATG16L1; IBD10; UNQ9393/PRO34307; WDR30
UniProt ID: (Human) Q676U5
Entrez Gene ID: (Human) 55054
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