|Immunohistochemistry (IHC)||10-50 µg/ml|
|Western Blot (WB)||10-50 µg/ml|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Sheep / IgG|
|Immunogen||A synthetic peptide from human cysteine protease ATG4C|
|Purification||Ammonium sulfate precipitation|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Reconstitute with 500 ul of distilled water.
Centrifuge to remove any insoluble material.
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: APG4 (ATG4) autophagy-related homolog C; APG4 autophagy 4 homolog C; APG4-C; APG4C; ATG4 autophagy related 4 homolog C; ATG4 autophagy related 4 homolog C (S. cerevisiae); ATG4C; AUT-like 1, cysteine endopeptidase; AUT-like 3 cysteine endopeptidase; AUTL1; AUTL3; autophagin 3; Autophagin-3; autophagy related 4C, cysteine peptidase; autophagy-related 4C; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C; Cysteine protease ATG4C; cysteine protease involved in autophagy; FLJ14867
Gene Aliases: APG4-C; APG4C; ATG4C; Atg4cl; AUTL1; AUTL3
Molecular Function: hydrolase
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