|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||Assay-Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 220 and 441 of Human ATG4D|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28363 targets ATG4D in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28363 immunogen is recombinant fragment corresponding to a region within amino acids 220 and 441 of Human ATG4D.
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: APG4 autophagy 4 homolog D; APG4-D; APG4D; ATG4 autophagy related 4 homolog D; AUT-like 4; AUT-like 4 cysteine endopeptidase; AUTL4; Autophagin-4; autophagy related 4D, cysteine peptidase; Autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; cysteine endopeptidase; Cysteine protease ATG4D; cysteine protease involved in autophagy
Gene Aliases: APG4-D; APG4D; ATG4D; AUTL4
UniProt ID: (Human) Q86TL0
Entrez Gene ID: (Human) 84971
Molecular Function: hydrolase
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