|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
PA1-21872 detects AXUD1 in human samples.
PA1-21872 has been successfully used in Western blot procedures.
PA1-21872 immunogen is AXUD1.
Axin, an important regulator of beta-catenin, is frequently mutated in human hepatocellular carcinomas (HCCs) and transduction of the wild-type Axin gene (AXIN1) induces apoptosis in HCC cells as well as in colon cancer cells. A novel gene, AXUD 1 (AXIN 1 up-regulated), has enhanced expression in response to exogenously expressed AXIN 1. It is expressed in all human tissues examined, most abundantly in lung, placenta, skeletal muscle, pancreas and leukocytes. Data suggests that AXUD 1 may have a tumor-supressor function in those organs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Axin-1 up-regulated gene 1 protein; AXIN1 up-regulated 1; AXUD1; CSRNP-1; Cysteine/serine-rich nuclear protein 1; DKFZp566F164; FAM130B; Protein URAX1; TAIP-3; TGF-beta-induced apoptosis protein 3; URAX1
Gene Aliases: AXUD1; CSRNP-1; CSRNP1; FAM130B; TAIP-3; TAIP3; URAX1
UniProt ID: (Human) Q96S65
Entrez Gene ID: (Human) 64651
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