|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||5-10 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from human adiponectin receptor 2.|
|Purification||Ammonium sulfate precipitation|
|Contains||0.08% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
A suggested positive control for this product is colon, hippocampus, or trachea lysate.
ADR2 functions as a receptor for globular and full-length adiponectin (APM1), which is an essential hormone secreted by adipocytes that acts as an antidiabetic. ADR2 is also probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. ADR2 mediates an increase in AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin and has some intermediate-affinity receptor activity for both globular and full-length adiponectin. ADR2 may form homo and heteromultimers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adiponectin receptor protein 2; AdipoR2; Progestin and adipoQ receptor family member II
Gene Aliases: ACDCR2; ADIPOR2; PAQR2
UniProt ID: (Human) Q86V24
Entrez Gene ID: (Human) 79602
Molecular Function: receptor
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