|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 172 and 448 of Human Aladin|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27197 targets Aladin in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-27197 immunogen is recombinant fragment corresponding to a region within amino acids 172 and 448 of Human Aladin.
The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AAA; AAASb; achalasia, adrenocortical insufficiency, alacrimia; ADRACALA; ADRACALIN; ALADIN; Allgrove; Allgrove, triple-A; triple-A
Gene Aliases: AAA; AAAS; AAASb; ADRACALA; ADRACALIN; ALADIN; GL003
UniProt ID: (Human) Q9NRG9
Entrez Gene ID: (Human) 8086
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