|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Western Blot (WB)||1:50-1:500|
|Immunohistochemistry (Paraffin) (IHC (P))||See 2 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Human p504s/AMACR polypeptide|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-14576 targets Alpha methylacyl-CoA-racemase in WB, IF and IHC (P) applications and shows reactivity with Human samples.
The MA5-14576 immunogen is human p504s/AMACR polypeptide.
Alpha methylacyl-CoA-racemase (AMACR), also known as p504s is an enzyme involved in the metabolism of branched-chain fatty acids. p504s is expressed in various normal tissues and carcinomas, while it is overexpressed over 30-fold in prostate carcinoma compared to benign glandular tissues1. When p504s is overexpressed in atypical glands without basal cells, it establishes a diagnosis of prostatic carcinoma. High-grade prostatic intraepithelial neoplasia, atypical adenomatous hyperplasia and urothelial carcinoma may also express p504s.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-methylacyl-CoA racemase; Alpha-methylacyl-CoA racemase
Gene Aliases: AMACR; AMACRD; CBAS4; RACE; RM
UniProt ID: (Human) Q9UHK6
Entrez Gene ID: (Human) 23600
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