|Immunohistochemistry (Paraffin) (IHC (P))||Neat|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the N-terminal region of the human protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.1% sodium azide|
|Storage conditions||4° C, do not freeze|
PA1-20917 detects Amylin in Human samples.
PA1-20917 has been successfully used in Immunohistochemistry (Paraffin) procedures.
PA1-20917 immunogen corresponds to Synthetic peptide corresponding to the N-terminal region of the human protein..
Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta amyloid (Abeta) assosciated with Alzheimer's disease, can induce apoptotic cell death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AMYLIN; DAP; Diabetes-associated peptide; Insulinoma amyloid peptide; Islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin)
Gene Aliases: DAP; IAP; IAPP
UniProt ID: (Human) P10997
Entrez Gene ID: (Human) 3375
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