|ELISA (ELISA)||Assay Dependent|
|Immunocytochemistry (ICC)||2 µg/ml|
|Immunofluorescence (IF)||2 µg/ml|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Immunohistochemistry (IHC)||See 7 publications below|
|Immunocytochemistry (ICC)||See 3 publications below|
|Immunohistochemistry (Frozen) (IHC (F))||See 2 publications below|
|Immunofluorescence (IF)||See 3 publications below|
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
|Tested Species reactivity||Dog, Human, Mouse, Rabbit, Rat|
|Published species reactivity||Dog , Pig , Rat , Fruit fly , Sheep , Hamster , Mouse , Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||A synthetic peptide derived from the spectrin-binding domain of the human ankyrin G protein.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
Ankyrin-G is found in several tissues including brain where, due to tissue-specific RNA processing, it is expressed as two different isoforms, localized to axon initial segments and nodes of Ranvier. Ankyrin-G is also found at sites of epithelial cell-cell contact and in the intracellular membranes of some cells. Ankyrin-G isoforms contain a unique stretch of sequence highly enriched in serine and threonine residues immediately following a globular head domain. Ankyrin-G is thought to participate in the maintenance and targeting of ion channels and cell adhesion molecules to the nodes of Ranvier and to axon initial segments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ANK-3; Ankyrin-3; Ankyrin-G; brain-specific ankyrin-G
Gene Aliases: 2900054D09Rik; AI314020; Ank-3; ANK3; AnkG; Ankyrin-3; ANKYRIN-G; MRT37
Molecular Function: cytoskeletal protein
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.