|Flow Cytometry (Flow)||3-5 µg/10^6 cells|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic Peptide: L(92) M K L T E D R E Q I R Q G L E(107) C|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-602 detects Tem-8 from mouse samples.
PA1-602 has been successfully used in Western blot and immunohistochemical procedures. By Western blot, this antibody detects ~45 kDa, 60 kDa, 85 kDa proteins, representing Tem-8 from mouse tissue extracts.This antibody has also been used in immunohistochemical procedures (paraffin samples) using mouse tissues.
PA1-602 immunizing peptide corresponds to amino acid residues 92-107, within the extracellular domain, of human ATR/TEM8. This peptide (Cat. # PEP-253) is available for neutralization and control experiments.
Anthrax Toxin Receptor (ATR), also known as Tem-8 is a single transmembrane domain containing protein which is alternately spliced for a short, medium and long form. The short form represents the secreted form of the protein. The mid-length form is also known as ATR (Anthrax Toxin Receptor) has known functions in the response to the lethal toxin from the anthrax bacteria. The long form is termed Tem-8 and has been shown to be involved in angiogenesis and the proteasomal degradation pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2310008J16Rik; 2810405N18Rik; Anthrax toxin receptor 1; ATR; Tem-8; Tumor endothelial marker 8
Gene Aliases: 2310008J16Rik; 2810405N18Rik; Antrx1; ANTXR1; ATR; GAPO; TEM8
Molecular Function: receptor
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.