|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 385 and 620 of Human Apc6|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27812 targets Apc6 in WB applications and shows reactivity with Human samples.
The PA5-27812 immunogen is recombinant fragment corresponding to a region within amino acids 385 and 620 of Human Apc6.
This gene encodes a component protein of the APC complex, which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein and two other APC complex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that may be involved in protein-protein interaction. Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ANAPC6; anaphase-promoting complex; Anaphase-promoting complex subunit 6; anaphase-promoting complex, subunit 6; APC6; CDC16 homolog; CDC16Hs; cell division cycle 16 homolog; Cell division cycle protein 16 homolog; CUT9; Cyclosome subunit 6; subunit 6
Gene Aliases: ANAPC6; APC6; CDC16; CDC16Hs; CUT9
UniProt ID: (Human) Q13042
Entrez Gene ID: (Human) 8881
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