|Western Blot (WB)||1:500|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human Apc7|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
For Western Blot, this antibody has non-specific bands at 39 kDa and 45 kDa.
This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome , a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Anaphase-promoting complex subunit 7; APC7; APC7, anaphase-promoting complex subunit 7; Cyclosome subunit 7; Prediabetic NOD sera-reactive autoantigen
Gene Aliases: ANAPC7; APC7; AW545589
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