|ELISA (ELISA)||Assay dependent|
|Western Blot (WB)||Assay dependent|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Mouse, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Purified mouse apolipoprotein AI from pooled mouse plasma high density lipoprotein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 8, with 1mM EDTA|
|Contains||0.02% sodium azide|
|Storage conditions||4° C, do not freeze|
PA1-23059 detects apolipoprotein A1 in mouse and rat samples. This antibody does not cross-react with human Apolipoprotein A1.
PA1-23059 has been successfully used in ELISA, Radial immunodiffusion assays, and Western blot procedures. Predicted molecular weight of 31 kDa.
The PA1-23059 immunogen is purified mouse apolipoprotein AI from pooled mouse plasma high density lipoprotein.
Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alp-1; Apo-AI; Apoa-1; apolipoprotein A-1; Apolipoprotein A-I; Apolipoprotein A1; Brp-14; Ltw-1; Lvtw-1; MGC102525; preproapolipoprotein A-I; Sep-1; Sep-2; Sep2
Gene Aliases: Alp-1; apo-AI; Apoa-1; apoA-I; Apoa1; Brp-14; Ltw-1; Lvtw-1; Sep-1; Sep-2; Sep2
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