|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 115-145 amino acids from the central region of human Aurora-C|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARK-3; Aurora 3; aurora B; Aurora kinase C; Aurora-C; aurora-related kinase 3; Aurora/IPL1-related kinase 3; aurora/Ipl1/Eg2 protein 1; Aurora/IPL1/Eg2 protein 2; epididymis secretory protein Li 90; serine/threonine kinase 13 (aurora/IPL-like); serine/threonine kinase 13 (aurora/IPL1-like); Serine/threonine protein kinase 13; Serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C
Gene Aliases: AIE1; AIE2; AIK3; AIRK3; ARK-3; ARK3; AurC; AURKC; aurora-C; HEL-S-90; IAK3; SPGF5; STK13
UniProt ID: (Human) Q9UQB9
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