|Immunohistochemistry (Paraffin) (IHC (P))||24 - 48 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 18 amino acid peptide from C-terminus of human BDKRB1.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Panda, Bovine, Horse (89%) Pig (83%).
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B1 bradykinin receptor; B1BKR; B1R; BDKRB1; Bk b1 receptor; BK-1 receptor; BKB1R; BKR1; BRADYB1; Bradykinin B1 receptor; Bradykinin receptor 1; Bradykinin receptor B1; bradykinin receptor B2; Kinin b1 receptor
Gene Aliases: B1BKR; B1R; BDKRB1; BDKRB2; BKB1R; BKR1; BRADYB1
UniProt ID: (Human) P46663
Entrez Gene ID: (Human) 623
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