|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 123 and 357 of Human B3GALT4|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-32072 targets B3GALT4 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-32072 immunogen is recombinant fragment corresponding to a region within amino acids 123 and 357 of Human B3GALT4.
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-galactosyltransferase; 3-galactosyltransferase 4; 3-GalTase 4; b3Gal-T4; beta-1; Beta-1,3-galactosyltransferase 4; Beta-1,3-GalTase 4; beta-3-galactosyltransferase 4; BETA3GALT4; Gal-T2; GALT2; GALT4; Ganglioside galactosyltransferase; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase 4; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4; UDP-galactose:beta-N-acetyl-galactosamine-beta-1; UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase
Gene Aliases: B3GALT4; BETA3GALT4; GALT2; GALT4
UniProt ID: (Human) O96024
Entrez Gene ID: (Human) 8705
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