|Western Blot (WB)||1-3 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (YEEGGKQCVERKCP) corresponding to the C-terminus amino acids of ACTL6A / ACTL6B|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology.
The protein encoded by this gene is a member of a family of actin-related proteins which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 53 kDa BRG1-associated factor A; 53 kDa BRG1-associated factor B; actin-like 6A; actin-like 6B; Actin-like protein 6A; Actin-like protein 6B; actin-related protein; actin-related protein 4; Actin-related protein Baf53a; Actin-related protein Baf53b; ACTL6; ACTL6A; ACTL6B; ARPN-BETA; ArpNalpha; ArpNbeta; BAF complex 53 kDa subunit; BAF53; BAF53A; BAF53B; BRG1-associated factor; BRG1-associated factor 53A; BRG1-associated factor 53B; hArpN alpha; hArpN beta; INO80 complex subunit K; INO80K; MGC5382 Arp4
Gene Aliases: ACTL6; ACTL6A; ACTL6B; Arp4; ARPN-BETA; arpNalpha; BAF53; BAF53A; BAF53B; INO80K
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