|Flow Cytometry (Flow)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1-2 µg/ml|
|Western Blot (WB)||1 µg/mL|
|Immunohistochemistry (IHC)||See 9 publications below|
|Western Blot (WB)||See 3 publications below|
|Tested Species reactivity||Human, Non-human primate|
|Published species reactivity||Rat Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||A Synthetic peptide, aa 41-54 (Cys-GAAPAPGIFSSQPG) of human bcl-2 protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-13663 targets BCL-2 alpha in FACS, IF, IHC (P), and WB applications and shows reactivity with Human and Non-human primate samples.
The MA5-13663 immunogen is a Synthetic peptide, aa 41-54 (Cys-GAAPAPGIFSSQPG) of human bcl-2 protein.
Expression of Bcl-2alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2alpha protein, whereas the normal or hyperplastic germinal centers are negative.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; BCL-2 alpha isoform; bcl-2-like protein 5; bcl-2-related protein A1; bcl2-L-5; hematopoietic BCL2-related protein A1; hemopoietic-specific early response protein; protein BFL-1; protein phosphatase 1, regulatory subunit 50
Gene Aliases: Bcl-2; BCL2; PPP1R50
UniProt ID: (Human) C9JHD5
Entrez Gene ID: (Human) 596
Molecular Function: signaling molecule
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