|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||1:5000|
|Tested Species reactivity||Dog, Human, Rat|
|Host / Isotype||Sheep / IgG|
|Contains||0.08% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-28275 detects Bcl2 from rat, canine, and human samples.
PA1-28275 has been successfully used in immunofluorescence, immunoprecipitation, and Western blot applications. A predicted molecular weight of approximately 29 kDa is expected.
The PA1-28275 immunogen is a proprietary sequence.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apoptosis regulator Bcl-2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl-2; Bcl2-like protein; protein phosphatase 1, regulatory subunit 50
Gene Aliases: BCL-2; BCL2; PPP1R50
Molecular Function: signaling molecule
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