|Western Blot (WB)||1-2 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 3-14 of human and mouse Bcl-XL and Bcl-XS.|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody is predicted to react with mouse based on sequence homology.
Suggested positive control: antigen standard for BCL2L1 (transient overexpression lysate), Jurkat, MOLT-4, or Rh-30.
The Bcl-2 family consists of anti-apoptotic (or cell survival) genes, such as Bcl-2, Bcl-XL and pro-apoptotic (or cell death) genes including Bax and BAD. The balance of expression between these genes may determine the death or survival of a cell. In addition to its anti-apoptotic effect, Bcl-X has two isoforms, resulting from alternative splicing. Bcl-XL (long) is a 241 amino acid protein (27 kD) and Bcl-XS is a 178 amino acid protein with predicted molecular weight of 19.5 kD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apoptosis regulator Bcl-X; Bcl-2-like protein 1; Bcl-X; bcl-xL; BCL-XL/S; bcl-xS; Bcl2-L-1; BCL2-like 1; BCL2L; BCLX; DKFZp781P2092; protein phosphatase 1, regulatory subunit 52
Gene Aliases: Bcl-X; BCL-XL/S; BCL2L; BCL2L1; BCLX; PPP1R52
UniProt ID: (Human) Q07817
Entrez Gene ID: (Human) 598
Molecular Function: signaling molecule
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