|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 160-189 amino acids from the C-terminal region of human BHLHA15|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 8; basic helix-loop-helix domain containing; basic helix-loop-helix domain containing, class B, 8; basic helix-loop-helix family, member a15; bHLHa15; BHLHB8; Class A basic helix-loop-helix protein 15; class B; Class B basic helix-loop-helix protein 8; class II bHLH protein MIST1; intestine and stomach expression 1; MIST-1; MIST1; muscle; Muscle, intestine and stomach expression 1
Gene Aliases: 1810009C13Rik; BHLHA15; BHLHB8; MIST-1; MIST1
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