|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 236-264 amino acids from the central region of human BHLHB5|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with chicken and mouse based on sequence homology.
BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. BHLHB5 despite the presence of an intact basic domain, does not bind to DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5; basic helix-loop-helix domain containing; basic helix-loop-helix domain containing, class B, 5; basic helix-loop-helix family, member e22; Beta3; BHLHB5; bHLHe22; CAGL85; class B; Class B basic helix-loop-helix protein 5; Class E basic helix-loop-helix protein 22; TNRC20; trinucleotide repeat containing 20; Trinucleotide repeat-containing gene 20 protein
Gene Aliases: Beta3; BHLHB5; BHLHE22; CAGL85; TNRC20
UniProt ID: (Human) Q8NFJ8
Entrez Gene ID: (Human) 27319
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