|Immunohistochemistry (Paraffin) (IHC (P))||1:200|
|Western Blot (WB)||1:500-1:200|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide within the extreme C-terminus of the human BACH1/Brip1 protein sequence.|
|Storage buffer||whole serum|
|Contains||0.01% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Suggested positive control: HeLa, Raji, 293, MCF7 and SKOV3 whole cell extracts.
BRIP1 (also called BACH1) is a helicase that interacts with the BRCT domain of BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 has recently been found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent of BRCA1 and downstream of FANCD2 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent RNA helicase BRIP1; BACH 1; BACH1 BRIP1; BRAC 1 Associated C Terminal Helicase 1; BRCA 1 Interacting Protein 1; BRCA1-associated C-terminal helicase 1; BRCA1-binding helicase-like protein BACH1; BRCA1-interacting protein 1; BRCA1-interacting protein C-terminal helicase 1; BRCA1/BRCA2-associated helicase 1; BRIP 1; FANCJ protein; Fanconi anemia group J protein; Fanconi anemia group J protein homolog; Protein FACJ
Gene Aliases: 3110009N10Rik; 8030460J03Rik; BACH1; BRIP1; FACJ; FANCJ; OF
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