|Western Blot (WB)||1:200-1:2000|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rat|
|Host / Isotype||Sheep|
|Immunogen||A synthetic peptide from human Beclin-1 conjugated to an immunogenic carrier protein|
|Storage buffer||whole serum|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Reconstitute with 150 ul of distilled water.
Centrifuge to remove any insoluble material.
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role in autophagy. Ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATG6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; Beclin-1; beclin1; BECN1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30
Gene Aliases: 4921513J16Rik; 5430417M23Rik; ATG6; beclin1; BECN1; GT197; VPS30
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