|Immunohistochemistry (Paraffin) (IHC (P))||1:150|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues in the amino-terminus of Bik|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with other Bcl-2 family members.
The protein encoded by this gene is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apoptosis inducer NBK; apoptosis-inducing NBK; Bcl-2-interacting killer; BCL2-interacting killer (apoptosis-inducing); BIP1; BP4; natural born killer
Gene Aliases: BIK; BIP1; BP4; NBK
UniProt ID: (Human) Q13323
Entrez Gene ID: (Human) 638
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