|Immunohistochemistry (Frozen) (IHC (F))||1:50-1:75|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:75|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic human gastrin releasing peptide (amino acid 14-27) coupled to BSA.|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.02M sodium phosphate, pH 7.3|
|Contains||0.05% sodium azide|
|Storage conditions||4° C, do not freeze|
PA1-29122 detects Bombesin from human samples.
PA1-29122 has been successfully used in immunohistochemistry (frozen tissue) and immunohistochemistry (paraffin tissue) applications.
The PA1-29122 immunogen is synthetic human gastrin releasing peptide (amino acid 14-27) coupled to BSA.
Bombesin is a 14 amino acid peptide originally isolated from the skin of a frog. It has two known homologues in mammals called neuromedin B and gastrin releasing peptide. It works on the gastrointestinal tract neuroendocrine hormone and it stimulates gastrin release from G cells. It activates three different G-protein coupled receptors known as BBR1 2 and 3. It also activates these receptors in the brain. Together with cholecystokinin it is the second major source of negative feedback signals that stop eating behaviour.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bombesin; Gastrin Releasing Peptide; Gastrin-releasing peptide; GRP; neuromedin C; pre-progastrin releasing peptide; prepro-GRP; testicular tissue protein Li 103
Gene Aliases: BN; GRP; GRP-10; preproGRP; proGRP
UniProt ID: (Human) P07492
Entrez Gene ID: (Human) 2922
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