|ELISA (ELISA)||1:2000 - 1:5000|
|Western Blot (WB)||1:2000 - 1:5000|
|Tested Species reactivity||Mouse|
|Host / Isotype||Chicken / IgY|
|Immunogen||Mouse C-reactive protein C-terminal peptide|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-9578 detects CRP in mouse samples. PA1-9578 may have some cross reaction with C reactive protein from rat, human and other mammalian species.
PA1-9578 has been successfully used in Western blot and ELISA procedures. By Western blot, PA1-9578 detects a 23 kDa protein representing CRP.
PA1-9578 immunogen is mouse C-reactive protein C-terminal peptide.
C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-reactive protein; C-reactive protein, petaxin related; CSRP; CYRP; D1S181E; DKFZp686M148
Gene Aliases: AI255847; Crp; Ptx1
UniProt ID: (Mouse) P14847
Entrez Gene ID: (Mouse) 12944
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