|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 310 and 553 of Human CACNB1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28900 targets CACNB1 in IF and WB applications and shows reactivity with Human and mouse samples.
The PA5-28900 immunogen is recombinant fragment corresponding to a region within amino acids 310 and 553 of Human CACNB1.
The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: beta 1 polypeptide; CAB1; CACNLB1; calcium channel; calcium channel beta-1 subunit; Calcium channel voltage-dependent subunit beta 1; calcium channel, L type, beta 1 polypeptide; calcium channel, voltage-dependent, beta 1 subunit; CCHLB1; dihydropyridine-sensitive L-type; dihydropyridine-sensitive L-type, calcium channel beta-1 subunit; L type; voltage-dependent calcium channel beta1 subunit; Voltage-dependent L-type calcium channel subunit beta-1
Gene Aliases: CAB1; CACNB1; CACNLB1; Cchb1; CCHLB1
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