|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 131 of Human CALML5|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31373 targets CALML5 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31373 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 131 of Human CALML5.
This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: calmodulin-like 5; Calmodulin-like protein 5; Calmodulin-like skin protein; CLSP
Gene Aliases: CALML5; CLSP
UniProt ID: (Human) Q9NZT1
Entrez Gene ID: (Human) 51806
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