|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide corresponding to residues in human CALY|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody detects endogenous protein at a molecular weight of 23 kDa.
Purity is >95% by SDS-PAGE.
Calcyon is a single transmembrane protein that interacts with D1 dopamine receptors. Dopamine is a neurotransmitter that regulates synaptic transmission involved in learning and memory. D1 receptors, the most abundant dopamine receptor in the central nervous system, appear to modulate the activity of D2 dopamine receptors, mediate various behavioural responses, and regulate neuron growth and differentiation. Calcyon is present in neuronal cell bodies and processes of the cortex and hippocampus, and it is especially abundant in pyramidal neurons. Interaction of Calcyon with D1 receptors results in a release of intracellular calcium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: calcyon D1 dopamine receptor-interacting protein (CALCYON); calcyon neuron-specific vesicular protein; calcyon protein; calcyon; D1 dopamine receptor-interacting protein; CALY; D1 dopamine receptor-interacting protein; dopamine receptor D1 interacting protein; DRD1IP; Neuron-specific vesicular protein calcyon
Gene Aliases: 0710001P07Rik; 1110004A22Rik; Calcyon; CALY; DRD1IP; NSG3
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