|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 157 and 333 of Human CAPG|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29981 targets CAPG in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-29981 immunogen is recombinant protein fragment corresponding to a region within amino acids 157 and 333 of Human CAPG.
This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Actin regulatory protein CAP-G; actin-capping protein GCAP39; actin-regulatory protein CAP-G; AFCP; capping protein (actin filament), gelsolin-like; epididymis secretory protein Li 66; gelsolin-like capping protein; macrophage capping protein; Macrophage-capping protein; MCP; myc basic motif homolog 1
Gene Aliases: AFCP; CAPG; gCap39; HEL-S-66; mbh1; MCP
UniProt ID: (Human) P40121
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