|Flow Cytometry (Flow)||1:200 - 1:400|
|Western Blot (WB)||1:500 - 1:2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human CBX8 (amino acids: 17-222) expressed in E. Coli.|
|Storage buffer||PBS with 0.5% proprietary stabilizer|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-17039 targets CBX8 in FACS, pep-ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17039 immunogen is purified recombinant fragment of human CBX8 (amino acids: 17-222) expressed in E. Coli.
MA5-17039 detects CBX8 which has a predicted molecular weight of approximately 43.4kDa.
Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chromobox homolog 8 (Pc class homolog, Drosophila); Chromobox protein homolog 8; Pc class 3 homolog; Pc3; polycomb 3; Polycomb 3 homolog; Rectachrome 1
Gene Aliases: CBX8; PC3; RC1
UniProt ID: (Human) Q9HC52
Entrez Gene ID: (Human) 57332
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