|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 21-52 amino acids from the N-terminal region of human CCK4 (PTK7)|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
CCK4 may function as a cell adhesion molecule. Although it belongs to the insuline receptor subfamily of the Tyr protein kinases, it likely lacks the catalytic activity of a tyrosine kinase. It may be connected to the pathophysiology of colon carcinomas and/or may represent a tumor progression marker. This Type I membrane protein is highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes, but weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle, and not in colon. It is also expressed in erythroleukemia cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CCK-4; Colon carcinoma kinase 4; Colon carcinoma kinase-4; Inactive tyrosine-protein kinase 7; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; PTK7; PTK7 protein tyrosine kinase 7; Tyrosine-protein kinase-like 7
Gene Aliases: CCK-4; CCK4; PTK7
UniProt ID: (Human) Q13308
Entrez Gene ID: (Human) 5754
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