|Immunohistochemistry (Paraffin) (IHC (P))||1:250|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide corresponding to residues E(4) Q N Q S T D Y Y Y E E N E M N G T Y D Y S Q Y E L I C(31) of human CCR11.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2, with 1mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-21616 detects CCR11 in Human and Mouse samples.
PA1-21616 has been successfully used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin) and Western Blot procedures.
The PA1-21616 immunogen is a synthetic peptide corresponding to residues E(4) Q N Q S T D Y Y Y E E N E M N G T Y D Y S Q Y E L I C(31) of human CCR11.
Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR11 in particular is expressed in the heart, lung, and small intestine. It binds members of the monocyte chemoattractant family including MCP-1, MCP-2, and MCP-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Atypical chemokine receptor 4; C-C chemokine receptor type 11; C-C CKR-11; CC chemokine receptor-like 1; CC-CKR-11; CCBP2; CCR-11; CCR10; CCR11; CCRL1; CCX CKR; CCX-CKR; chemocentryx chemokine receptor; chemokine (C-C motif) receptor-like 1; chemokine (C-C) receptor-like 1; chemokine receptor CCR11; chemokine, cc motif, receptor-like protein 1; CKR-11; orphan seven-transmembrane receptor, chemokine related; PPR1; VSHK1
Gene Aliases: A630091E18Rik; ACKR4; CC-CKR-11; CCBP2; CCR-11; CCR10; CCR11; CCRL1; CCX CKR; CCX-CKR; CCX-CKR1; CKR-11; Cmkbrl1; PPR1; VSHK1
Molecular Function: cell adhesion molecule cytokine receptor defense/immunity protein hydrolase immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule phosphatase protein phosphatase receptor
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