|Flow Cytometry (Flow)||1-3 µl for 10^6 cells in 100 µl|
|Immunohistochemistry (Paraffin) (IHC (P))||1:500|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide corresponding to residues D(8)TTQDETVYNSYYFYESMP(26)C of Mouse CCR4|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2, with 1mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-29771 detects CCR4 from mouse samples.
PA1-29771 has been successfully used in flow cytometry, immunocytochemistry, immunohistochemistry (paraffin tissue), and Western blot applications. A suggested positive control for this product is mouse spleen cells.
The PA1-29771 immunogen is a synthetic peptide (DTTQDETVYNSYYFYESMPC) corresponding to amino acids 8-26 of Mouse CCR4.
Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-C chemokine receptor type 4; C-C CKR-4; CC-CKR-4; CD194; chemokine (C-C) receptor 4; ChemR13; CKR4; CMKBR4; fusin; HGCN:14099; leukocyte-expressed seven-transmembrane-domain receptor; MGC88293
Gene Aliases: C-C CKR-4; Ccr4; CHEMR1; Cmkbr4; LESTR; Sdf1r
UniProt ID: (Mouse) P51680
Entrez Gene ID: (Mouse) 12773
Molecular Function: G-protein coupled receptor cell adhesion molecule cytokine receptor defense/immunity protein hydrolase immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule phosphatase protein phosphatase receptor
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