|Flow Cytometry (Flow)||1-3 µl for 10^6 cells in 100 µl|
|Immunohistochemistry (Paraffin) (IHC (P))||1:250|
|Western Blot (WB)||1:1000|
|Miscellaneous PubMed (MISC)||See 1 publications below|
|Immunohistochemistry (IHC)||See 3 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide corresponding to residues CLATEDADSENSSFYYYDYLDEVAFML of human CCRD6.|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M potassium phosphate, pH 7.2, with 0.14M NaCl, 1mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-21614 detects Chemokine Receptor D6 in human samples.
PA1-21614 has been successfully used in ELISA, FACS, immunocytochemistry, immunohistochemistry (paraffin) and Western blot procedures.
The PA1-21614 immunogen is a synthetic peptide corresponding to residues CLATEDADSENSSFYYYDYLDEVAFML of human CCRD6.
Peptide sequence is <50 % identical to other human chemokine receptors in this region.
This gene encodes a beta chemokine receptor similar to G protein-coupled receptors. Chemokines and the receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unkown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Atypical chemokine receptor 2; C-C chemokine receptor D6; CC-chemokine-binding receptor JAB61; chemokine (C-C motif) receptor 9; chemokine (C-C) receptor 9; chemokine binding protein 2; Chemokine receptor CCR-10; Chemokine receptor CCR-9; Chemokine Receptor D6; Chemokine-binding protein 2; Chemokine-binding protein D6
Gene Aliases: ACKR2; CCBP2; CCR10; CCR9; CMKBR9; D6; hD6
UniProt ID: (Human) O00590
Entrez Gene ID: (Human) 1238
Molecular Function: G-protein coupled receptor cell adhesion molecule cytokine receptor defense/immunity protein hydrolase immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule phosphatase protein phosphatase receptor
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