|Immunohistochemistry (Paraffin) (IHC (P))||24 - 32 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 19 amino acid peptide from 2nd cytoplasmic domain of human CCRL1.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey, Rat, Bovine (84%).
Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR11 in particular is expressed in the heart, lung, and small intestine. It binds members of the monocyte chemoattractant family including MCP-1, MCP-2, and MCP-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Atypical chemokine receptor 4; C-C chemokine receptor type 11; C-C CKR-11; CC chemokine receptor-like 1; CC-CKR-11; CCR-11; CCR11; CCRL1; CCX CKR; CCX-CKR; chemocentryx chemokine receptor; chemokine (C-C motif) receptor-like 1; chemokine, cc motif, receptor-like protein 1; CKR-11; orphan seven-transmembrane receptor, chemokine related; PPR1; VSHK1
Gene Aliases: ACKR4; CC-CKR-11; CCBP2; CCR-11; CCR10; CCR11; CCRL1; CCX CKR; CCX-CKR; CKR-11; PPR1; VSHK1
UniProt ID: (Human) Q9NPB9
Entrez Gene ID: (Human) 51554
Molecular Function: cell adhesion molecule cytokine receptor defense/immunity protein hydrolase immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule phosphatase protein phosphatase receptor
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