|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human CCRL2|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 10% glycerol, 1% BSA|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28743 targets CCRL2 in WB applications and shows reactivity with mouse samples.
The PA5-28743 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 45 of Human CCRL2.
This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: atypical chemokine receptor 5; C-C chemokine receptor-like 2; chemokine (C-C motif) receptor-like 2; Chemokine receptor CCR11; Chemokine receptor X; CKRX; CRAM-A; CRAM-B; G-protein coupled beta chemokine receptor; L-CCR; Lipopolysaccharide-inducible C-C chemokine receptor; Putative MCP-1 chemokine receptor
Gene Aliases: 1810047I05Rik; ACKR5; CCR11; CCR6; CCRL2; CKRX; Cmkbr1l2; CRAM; CRAM-A; CRAM-B; E01; HCR; L-CCR; Lccr
Molecular Function: G-protein coupled receptor cell adhesion molecule cytokine receptor defense/immunity protein hydrolase immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule phosphatase protein phosphatase receptor
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