|Flow Cytometry (Flow)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||White blood cells.|
|Conjugate||FITC , PE|
|Storage buffer||PBS with 0.2% carrier protein|
|Contains||0.08% sodium azide|
|Storage conditions||4° C, do not freeze|
This antibody is a monoclonal mixture of FITC-conjugated CD10 (clone RXB.14, isotype IgG1) and PE-conjugated CD19 (clone 1G9, isotype IgG1).
Anti-hCD10 recognizes a human common acute lymphoblastic antigen (CALLA), MW 100 kDa. The CD10 antigen is identical to human membrane-associated neutral endopeptidase (NEP;EC 22.214.171.124), also known as enkephalinase. The CD10 antigen is found on lymphocytes from patients with acute B-lymphoid leukemia. The antigen is also present on a wide variety of normal and neoplastic cell types including renal epithellum, fibroblasts, granulocytes and some lymphoma, melanoma and glioma cell lines. Identification of CD19 PE human B cells associated approximately 10% of peripheral blood lymphocytes expressing the 95,000 M.W. surface antigen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Atriopeptidase; AW495831; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; CALLA; CD10; CD19; Common acute lymphocytic leukemia antigen; Differentiation antigen CD19; Enkephalinase; membrane metallo-endopeptidase; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); membrane metallo-endopeptidase neutral endopeptidase; membrane metallo-endopeptidase variant 1; membrane metallo-endopeptidase variant 2; NEP; Neprilysin; neprilysin-390; neprilysin-411; Neutral endopeptidase 24.11; SFE; Skin fibroblast elastase; T-cell surface antigen Leu-12
Gene Aliases: B4; CALLA; CD10; CD19; CMT2T; CVID3; EPN; MME; NEP; SFE
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