|Flow Cytometry (Flow)||1 ug/1 million cells|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Flow Cytometry (Flow)||See 2 publications below|
|Tested Species reactivity||Rat|
|Published species reactivity||Cat|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Phytohaemagglutinin-activated rat lymph node cells.|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-70020 detects CD134 in rat samples.
MA1-70020 has been successfully used in flow cytometry, immunoprecipitation and immunohistochemistry (frozen sections) procedures.
The MA1-70020 immunogen is Phytohaemagglutinin-activated rat lymph node cells.
CD134, also known as OX40, is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naïve T cells, unlike CD28. OX40 is a secondary costimulatory molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD134; cluster designation 134; MRC OX40; OX40 antigen; OX40L receptor; Tax-transcriptionally activated glycoprotein 1; TNFRSF4; tumor necrosis factor (ligand) superfamily member 4; Tumor necrosis factor receptor superfamily member 4; tumor necrosis factor superfamily, member 4
Gene Aliases: Ox40; Tnfrsf4; Txgp1; Txgp1l
UniProt ID: (Rat) P15725
Entrez Gene ID: (Rat) 25572
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