|ELISA (ELISA)||Assay Dependent|
|Flow Cytometry (Flow)||1:100 -1:200|
|Functional Assay (FN)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Flow Cytometry (Flow)||See 12 publications below|
|Miscellaneous PubMed (MISC)||See 33 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Tested Species reactivity||Bovine, Dog, Camelid, Cat, Goat, Human, Mink, Non-human primate, Sheep, Pig, Rabbit|
|Published species reactivity||Non-human primate , Human Rhesus monkey|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||The details of the immunogen for this antibody are not currently available.|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This product is a low-endotoxin, preservative-free formulation. Endotoxin level is <0.01 EU/ug.
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor; it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD14; CD14 antigen; Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein
Gene Aliases: BOS_8248; CD14
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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