|ELISA (ELISA)||5-10 µg/mL|
|Western Blot (WB)||5-10 µg/mL|
|Tested Species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Human Tissue Factor.|
|Purification||Ion-exchange chromatography, Ammonium sulfate precipitation|
|Storage buffer||50% water with 50% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-43058 detects Tissue Factor in human samples.
PA1-43058 has successfully been used in Western blot and ELISA applications.
PA1-43058 was derived from human tissue factor.
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD142; Coagulation factor 3; Coagulation factor III; coagulation factor III (thromboplastin, tissue factor); F3; TF; TFA; Thromboplastin; Tissue factor
Gene Aliases: CD142; F3; TF; TFA
UniProt ID: (Human) P13726
Entrez Gene ID: (Human) 2152
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.