|Flow Cytometry (Flow)||Neat|
|Tested Species reactivity||Pig|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Porcine peripheral blood leucocytes.|
|Storage buffer||PBS with 1% BSA, 5% sucrose|
|Contains||0.09% sodium azide|
|Storage conditions||4° C, store in dark, DO NOT FREEZE!|
Clone G7 has been reported to block PBL-mediated antibody-dependent cell cytotoxicity (ADCC) and partially inhibit PMN-mediated ADCC.
Reconstitute with 1 ml of distilled water. After reconstitution, store product undiluted at 4°C in the dark.
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
CD16, a 50-65kDa cell surface molecule, is the low-affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD16A; CD16B; cytolytic trigger molecule G7; Fc gamma Receptor 3; Fc gamma Receptor III; fc-gamma RIII; FcgammaRIII a.1; FCGR3; FCGR3A; FCGR3B; FCGRIII; FCR-10; FCRIII; FCRIIIA; igG Fc receptor III; low affinity immunoglobulin gamma Fc region receptor III; RP11-5K23.1
Gene Aliases: FCGR3
Entrez Gene ID: (Pig) 397684
Molecular Function: cell adhesion molecule
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