|Flow Cytometry (Flow)||Neat|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgM|
|Storage buffer||PBS with 0.2% BSA|
|Contains||0.1% sodium azide|
|Storage conditions||4°C or -20°C if preferred, store in dark|
For FACS analysis, use 20ul of the suggested working dilution to label 5x10^5 cells in 100ul.
CD16 (also known low affinity Fc gamma receptor III for IgG (FcgammaRIII) or Leu 11) exists as a polypepetide-anchored from (FCgammaRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcgammaRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2. CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD16a; CD16a antigen; CD16b; Fc fragment of IgG low affinity IIIa receptor; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma Receptor 3b; Fc gamma receptor III-A; Fc gamma Receptor III-b; Fc gamma receptor IIIa; Fc gamma receptor IIIb; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD 16); Fc-gamma receptor IIIb (CD16); Fc-gamma RIII; Fc-gamma RIII-alpha; Fc-gamma RIII-beta; Fc-gamma RIIIa; fc-gamma RIIIb; FCG3; FcgammaRIIIA; FCGR3; FCGR3B; FcR-10; IgG Fc receptor III-1; IgG Fc receptor III-2; immunoglobulin G Fc receptor III; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; neutrophil-specific antigen NA
Gene Aliases: CD16; CD16A; CD16B; FCG3; FCGR3; FCGR3A; FCGR3B; FCGRIII; FCR-10; FCRIII; FCRIIIA; FCRIIIb; IGFR3; IMD20
Molecular Function: cell adhesion molecule
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.