|Flow Cytometry (Flow)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Flow Cytometry (Flow)||See 3 publications below|
|Miscellaneous PubMed (MISC)||See 2 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Thymus cells, Jurkat (T cell line)|
|Storage buffer||PBS, pH 7.2|
|Contains||0.1% sodium azide|
|Storage conditions||4° C|
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: b polypeptide; BDCA1; c polypeptide; CD1; CD1A; CD1b; CD1B antigen; CD1B antigen, b polypeptide; CD1c; CD1C antigen; CD1C antigen, c polypeptide; cortical thymocyte antigen CD1B; cortical thymocyte antigen CD1C; differentiation antigen CD1-alpha-3; R1; R7; RP11-101J8.3; RP11-101J8.4; T-cell surface glycoprotein CD1b; T-cell surface glycoprotein CD1c
Gene Aliases: BDCA1; CD1; CD1A; CD1B; CD1C; R1; R7
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