|Flow Cytometry (Flow)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1/IgG2a|
|Immunogen||T lymphocytes activated by mixed lymphocyte culture and LB lymphoblastoid cell line|
|Conjugate||FITC , PE|
|Storage buffer||PBS with 0.2% carrier protein|
|Contains||0.08% sodium azide|
|Storage conditions||4° C, do not freeze|
This antibody is a monoclonal mixture of FITC-conjugated CD2 (clone T6.3, isotype IgG2a) and PE-conjugated CD20 (clone DFA-7, isotype IgG1).
CD2 is found on the majority of human T and NK cells. CD2 presents on 78+8% normal peripheral lymphocytes and 100% of thymocytes. This antibody detects CD2 antigen CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lamda light chains. It appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation. It is expressed in all B cell precursor leukemias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2CD2 antigen; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; CD2; CD20; CD20 antigen; CD20 receptor; Erythrocyte receptor; LEU-16; Leukocyte surface antigen Leu-16; LFA-2; LFA-3 receptor; lymphocyte-function antigen-2; Membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; MGC3969; MS4A1; Rosette receptor; sheep red blood cell receptor; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5
Gene Aliases: B1; Bp35; CD2; CD20; CVID5; LEU-16; LFA-2; MS4A1; MS4A2; S7; SRBC; T11
Molecular Function: receptor
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