|Flow Cytometry (Flow)||0.25-0.5 ug per 1x10^6 cells|
|Miscellaneous PubMed (MISC)||See 8 publications below|
|Blocking Assay (BLOCK)||See 2 publications below|
|Tested Species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Syrian hamster / IgG|
|Immunogen||Mouse T lymphoma EL-4 cells.|
|Contains||0.1% sodium azide|
|Storage conditions||4° C|
CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. It is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes (approximately 95% of CD4+ cells and 50% of CD8+ cells). Mature thymocytes exhibit higher levels of CD28 than the immature cells. Activation of T cells results in enhanced CD28 expression. T cell activation requires two combined signals provided by antigen presenting cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD28; CD28 antigen; MGC138290; T-cell-specific surface glycoprotein CD28; Tp44
Gene Aliases: Cd28
UniProt ID: (Mouse) P31041
Entrez Gene ID: (Mouse) 12487
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