|Flow Cytometry (Flow)||20 ul/10^6 cells|
|Flow Cytometry (Flow)||See 1 publications below|
|Tested Species reactivity||Human, Non-human primate|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Immunogen||DC188.8.131.52 murine T cell hybridoma transfected with human CD28 cDNA.|
|Storage buffer||PBS with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage conditions||4° C, store in dark, DO NOT FREEZE!|
CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD28; CD28 antigen; MGC138290; T-cell-specific surface glycoprotein CD28; TP44
Gene Aliases: CD28; Tp44
UniProt ID: (Human) P10747
Entrez Gene ID: (Human) 940
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