|Immunohistochemistry (Paraffin) (IHC (P))||Neat|
|Western Blot (WB)||Neat-1:100|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Mixed / IgG2a|
|Immunogen||synthetic 13-mer peptide corresponding to aa 156-168 of the epsilon chain of human CD3 protien; CD20- Human tonsil B cells|
|Storage buffer||tris HCl, pH 7.6, with proprietary stabilizer|
|Contains||<0.1% sodium azide|
|Storage conditions||4° C|
MA5-14433 targets CD3/CD20 in IHC (P) and WB applications and shows reactivity with Human, Mouse and Rat samples. CD3 (clone SP7) is a rabbit monoclonal IgG antibody. CD20 (clone L26) is an IgG2a mouse monoclonal antibody.
The MA5-14433 immunogen is synthetic 13-mer peptide corresponding to aa 156-168 of the epsilon chain of human CD3 protein; the CD20 immunogen is human tonsil B cells.
The CD3 antibody reacts with the intracytoplasmic portion of the CD3 antigen expressed by normal and neoplastic T-lymphocytes. It stains human T-lymphocytes in both cortex and medulla of the thymus and in peripheral lymphoid tissues. CD20 is a non-Ig differentiation antigen of B-lymphocytes and the expression of CD20 is restricted to normal and neoplastic B-lymphocytes, being absent from all other leukocytes and tissues. The CD3-CD20 cocktail reveals lymphoid architecture in neoplastic situations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; CD20; CD20 antigen; CD20 receptor; CD3 antigen delta polypeptide; CD3 antigen, delta subunit; CD3 antigen, gamma polypeptide; CD3 delta; CD3 epsilon; CD3 gamma-chain; CD3 molecule delta polypeptide; CD3 molecule, gamma polypeptide; CD3-epsilon; CD3d; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule, delta (CD3-TCR complex); CD3e; CD3e antigen; CD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule, epsilon (CD3-TCR complex); CD3g; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); epsilon polypeptide TiT3 complex; epsilon subunit of T3; FLJ18683; LEU-16; Leukocyte surface antigen Leu-16; Lymphocyte antigen 44; Membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; membrane-spanning 4-domains, subfamily A, member 2; MGC3969; MS4A1; OKT3, delta chain; T-cell antigen receptor complex; T-cell antigen receptor complex, epsilon subunit of T3; T-cell antigen receptor complex, gamma subunit of T3; T-cell receptor T3 delta chain; T-cell receptor T3 gamma chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain; T3E; TCRE
Gene Aliases: AA960661; AI504783; B1; Bp35; CD20; CD3; CD3-DELTA; CD3-GAMMA; CD3D; CD3E; CD3epsilon; CD3G; Ctg-3; Ctg3; CVID5; IMD17; IMD18; IMD19; LEU-16; Ly-44; MS4A1; MS4A2; S7; T3D; T3E; T3G; TCRE
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