|Flow Cytometry (Flow)||Neat|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Immunohistochemistry (IHC)||See 21 publications below|
|Tested Species reactivity||Human, Non-human primate|
|Published species reactivity||Rabbit Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human endothelial cell membrane vesicles|
|Storage buffer||PBS with 1% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
This antibody does not react with bovine, dog, rat or sheep.
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
CD34 is possibly a adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD34; CD34 antigen; Hematopoietic progenitor cell antigen CD34; Mucosialin; RP11-328D5.2
Gene Aliases: CD34
UniProt ID: (Human) P28906
Entrez Gene ID: (Human) 947
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.